We are pleased to share the event “In silico approaches to phenotypic assays”, which will be held on November 19th 2020, at 4 PM CET.
Three Key Opinion Leaders of the field will partecipate at the webinar: discover who they are at the Biographies Page.
Phenotypic screening is used to identify substances that alter the phenotype of a cell or an organism. It has been a historical basis for the discovery of new drugs and in biological research and only after compounds were tested positive, biological targets are determined. While most drugs with novel mechanisms of action come from phenotypic screening, it is also of interest in the area of drug repositioning. Assembling the best libraries and selecting the best computer-aided drug design (CADD) techniques are of paramount importance to maximize the probabilities to select the best candidate following a phenotypic screening strategy.
Ligand based techniques and Artificial Intelligence are the best approach to guide a phenotypic based drug discovery process from a rational point of view.